![]() ![]() Johnson & Volpes Patterns & Experiments in Developmentalīiology. This experiment attempts to repeat Spemann and Mangold's experiment in Xenopus embryos. They used this information to induce the growth of a second neural tube on an already developing embryo. In 1924 Hans Spemann and Hilde Mangold showed that cells transplanted from this "organizer" region of the blastopore lip of one embryo will induce gastrulation in any kind of tissue. dorsal lip: noun the margin of the fold of blastula wall that delineates the dorsal limit of the blastopore, constitutes the primary organizer, and forms the point of origin of chordamesoderm. This area in the amphibian embryo has since been termed the organizer for its role in cell fate determination. that the dorsal lip of their early gastrula has the capacity of induction and organization of presumptive neural ectoderm to form a neural tube and also the capacity of evocation and organization of ectoderm, mesoderm and endoderm to form a complete secondary embryo. However, previous experiments show that cells in one area of the developing embryo are determined before gastrulation. The dorsal lip of the blastopore is a structure that forms during early embryonic development and is important for its role in organizing the germ layers.1 The dorsal lip is formed during early gastrulation as folding of tissue along the involuting marginal zone of the blastocoel forms an opening known as the blastopore. In early stages of development in amphibian embryos, very few cells' fates are rigidly determined. Marie Nickle, Franklin and Marshall College, Class of 2001 Dorsal Lip Transplant in Amphibian Embryos
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